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Blythe Masters has seen the future before, and Wall Street followed. Will it happen again?

If the development of virtual currencies is the story of a long cultural struggle between the idealistic hackers who founded them and the incumbent powers of the financial industry, this year has already seen established money strike two major blows. In March, San Francisco Bitcoin firm 21 emerged from stealth mode to announce a $116 million round of venture funding, the largest ever by a company in the digital currency sector. But it was the announcement of Wall Street pioneer Masters, 46, as CEO of Digital Asset Holdings — a New York start-up with fewer than 20 employees that has yet to launch a single product — around the same time that really caught the attention of the investment world.

Digital currency businesses are now a serious destination for venture capital: $350 million was poured into the sector in 2014, and $230 million has already been invested this year, according to London-based data firm CoinDesk.

But while VCs have been busy pumping cash into Bitcoin, the big beasts of Wall Street have mostly stayed on the sidelines. The appointment of Masters, who spent 27 highly successful years at JPMorgan Chase & Co. before leaving the firm last year after overseeing the sale of its commodities unit, changes that.

Digital Asset was launched late last year by finance veterans Sunil Hirani and Don Wilson; funding for the venture has come from the founders’ own pockets as well as friends and family, says Masters. It’s perhaps no accident that in the weeks since her new job was made public, several big banks have announced digital currency initiatives. In early April, for instance, UBS said it was starting a new innovation lab to explore financial applications of the blockchain, the infrastructure on which Bitcoin is built.

Bitcoin, launched in 2009, is the oldest and best known piece of a thriving global network of digital currencies. Digital Asset — which, unlike other new entrants in the sector, has no designs on being a trading business or an exchange — will focus not on these currencies as currencies. Instead, Masters says the company will exploit the distributed databases that are their structural core to build a software service that will effect “quicker, cheaper, more secure” settlement of trading in mainstream and digital assets.

The youngest woman to achieve the title of managing director in JPMorgan’s history, Masters helped create the derivatives market, which came to dominate institutional trading through the 1990s and 2000s. Her status as the “inventor” of credit default swaps, the trigger instrument for the collapse of American International Group, has made her a sometimes controversial figure. But Masters, who was born and raised in the U.K. and studied economics at Cambridge University, says her experience of the financial crisis and the ensuing debate over reform has convinced her of the need for something to replace the “old-fashioned infrastructure” that Wall Street uses to settle trades.